Structural characteristics of alkaline phosphatase from the moderately halophilic bacteriumHalomonassp. 593

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Structural characteristics of alkaline phosphatase from the moderately halophilic bacterium Halomonas sp. 593

Alkaline phosphatase (AP) from the moderate halophilic bacterium Halomonas sp. 593 (HaAP) catalyzes the hydrolysis of phosphomonoesters over a wide salt-concentration range (1-4 M NaCl). In order to clarify the structural basis of its halophilic characteristics and its wide-range adaptation to salt concentration, the tertiary structure of HaAP was determined by X-ray crystallography to 2.1 Å re...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section D Biological Crystallography

سال: 2014

ISSN: 1399-0047

DOI: 10.1107/s1399004713033609